Nathan Stitziel

Nathan O. Stitziel, MD, PhD

Instructor in Medicine, Cardiovascular Division, Washington University School of Medicine; Director, Center for Cardiovascular Genetics

Contact Information:

Mailing address:

660 S. Euclid Avenue, Campus Box 8086

St. Louis, MO 63110


Administrative Office:

Northwest Tower, Suite 13110

Phone: 314-362-1076

Fax: 314-747-8170

Laboratory Office:

4444 Forest Park Avenue, Room 6307


Education and Training:


1998: B.A. (Mathematics and Physics), Washington University, St. Louis, MO


2006: M.D., University of Illinois, Chicago, IL

2006: Ph.D. (Bioinformatics), University of Illinois, Chicago, IL


2006 – 2008: Internal Medicine Residency / Physician Scientist Development Program, University of Chicago, Chicago, IL

2008 – 2012: Cardiovascular Medicine Fellowship, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

2010 – 2012: Postdoctoral Fellowship, Brigham and Women’s Hospital, Massachusetts General Hospital, Broad Institute, Boston, MA

2011 – 2012: Clinical Fellow, Cardiovascular Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

2012: Instructor in Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA

2012 – Present: Instructor in Medicine, Washington University School of Medicine, St. Louis, MO


Honors and Awards:

B.A. with honors, Washington University, 1998

Williamson award (best medical student in Internal Medicine), University of Illinois, 2006

Radulovacki award (best research in the basic sciences), University of Illinois, 2006

Alpha Omega Alpha, University of Chicago, 2007

Eugene Braunwald Fellow in Cardiovascular Medicine, Brigham and Women’s Hospital, 2010 – 2011


Clinical Expertise:

Cardiovascular Genetics; inherited cardiovascular disease; genetic syndromes; cardiomyopathy and arrhythmia genetics


Research Interests:

Naturally occurring human genetic variation has proven to be a powerful tool for uncovering causal genes and pathways in a variety of cardiovascular disorders. Despite substantial progress in gene mapping, however, the majority of the inherited basis for complex cardiovascular traits remains unexplained. Recently developed techniques allowing for low-cost interrogation of the entire genome are now ushering in a new era of genetic studies. New analytic challenges are simultaneously being uncovered as we face the daunting task of interpreting and translating increasingly large amounts of complex genetic data.

Our research sits at the intersection of computational biology and human genetics to face these challenges in studying the inherited basis of cardiovascular disease. Using a variety of techniques in genomics and bioinformatics, my laboratory is interested in:  1) Identifying novel genes and pathways underlying both Mendelian and complex forms of disease; 2) Developing innovative computational methods for the analysis of complex genetic data; and 3) Applying insights gained from human genetics to improve patient care.



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