Population-wide linkage screen for successful aging in the Amish

Population-wide linkage screen for successful aging in the Amish
  • As the population ages, age-related disability will increasingly become an important public health concern.
  • Conventional linkage analysis only utilizes a small subset of the available genotype and pedigree information available in the Amish population, leading to lowered statistical power and potential false-negative results
  • Here, we present the use of dense genotypes to identify regions linked to successful aging at the population level